2,2',3,5'-Tetrabromodiphenyl ether CAS 446254-20-2
| CAS No. | 446254-20-2 |
| Molecular Formula | C12H6Br4O |
| Molecular Weight | 485.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2',3,5'-Tetrabromodiphenyl ether.
CATO supplies 2,2',3,5'-Tetrabromodiphenyl ether (CAS 446254-20-2), a certified reference material (molecular formula C12H6Br4O, MW 485.79 g/mol) for analytical method development and quality control.
The molecular framework of 2,2',3,5'-Tetrabromodiphenyl ether (C12H6Br4O) is characterized by a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H6Br4O |
| Molecular Weight | 485.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
Related Tetrabromodiphenyl Standards
- 3,3',5,5'-Tetrabromodiphenyl Ether (CAS 103173-66-6)
- 2,4,4',6-Tetrabromodiphenyl Ether (CAS 189084-63-7)
- 2,2',3,4'-Tetrabromodiphenyl Ether (CAS 446254-18-8)
- 2,2',3,4-Tetrabromodiphenyl ether (CAS 337513-68-5)
- 2,2',3,5-Tetrabromodiphenyl ether (CAS 446254-19-9)
- 2,2',3,6'-Tetrabromodiphenyl Ether (CAS 446254-22-4)
- 2,2',4,5'-Tetrabromodiphenyl Ether (CAS 243982-82-3)
- 2,2',4,5-Tetrabromodiphenyl Ether (CAS 337513-55-0)
Recommended Standards
- 1-(3,5-Dimethylphenyl)-3-(5-phenyl-1-(2,4,6-trichlorophenyl)-1H-pyrazol-4-yl)urea (CAS 477713-90-9)
- PBDE No. 51 (CAS 189084-57-9)
- 2,2',4,6-Tetrabromodiphenyl Ether (CAS 446254-23-5)
- 2,2',5,5'-Tetrabromodiphenyl ether (CAS 446254-24-6)
- 2-Methoxyethyl 6-amino-5-cyano-2-methyl-4-(o-tolyl)-4H-pyran-3-carboxylate (CAS 865612-58-4)
- 5’-METHOXYSPIRO[CYCLOPROPANE-1,1’-ISOINDOLIN]-3’-ONE (CAS 1007455-35-7)
- cyclobutylmethanesulfonamide (CAS 445305-92-0)
- 4-Hydroxy-3-methoxycinnamaldehyde (CAS 458-36-6)
- 1-methyl-1,2,3,4-tetrahydropyrazine-2,3-dione (CAS 4774-11-2)
- (S)-5-((1H-Indol-2-yl)methyl)-3-phenyl-2-thioxoimidazolidin-4-one (CAS 139614-40-7)
- 2-(Benzylthio)-1,4,5,6-tetrahydropyrimidine (CAS 6497-88-7)
- 1-(3-Chloro-phenyl)-pentan-1-one (CAS 42916-71-2)
- 3-Methyl-1-(2-phenylethyl)-4-piperidone (CAS 129164-39-2)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com