6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide CAS 446268-22-0
| CAS No. | 446268-22-0 |
| Molecular Formula | C5H7N3O4S |
| Molecular Weight | 205.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide (CAS 446268-22-0), a certified reference material (molecular formula C5H7N3O4S, MW 205.19 g/mol) for analytical method development and quality control.
The molecular framework of 6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide (C5H7N3O4S) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7N3O4S |
| Molecular Weight | 205.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 7-Fluoro-2-methylquinoline-4-carboxylic acid (CAS 915923-73-8)
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- Tert-butyl (1-methyl-1H-pyrazol-4-yl)carbamate (CAS 796845-64-2)
- Methyl 4-amino-5-bromopyrrolo[2,1-f][1,2,4]triazine-7-carboxylate (CAS 2092425-70-0)
- Dichloroethane (CAS 1300-21-6)
- Ethyl 4-cyanopiperidine-4-carboxylate (CAS 123755-34-0)
- (6-Bromo-3-(difluoromethyl)-5-iodopyridin-2-yl)methanol (CAS 1805245-87-7)
- Ketorolac Pyrrole Ester Impurity (CAS 4778-25-0)
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