1-(2-Amino-5,6,7,8-tetrahydroquinazolin-4-yl)-3-phenylthiourea CAS 446277-61-8
| CAS No. | 446277-61-8 |
| Molecular Formula | C15H17N5S |
| Molecular Weight | 299.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-Amino-5,6,7,8-tetrahydroquinazolin-4-yl)-3-phenylthiourea is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2-Amino-5,6,7,8-tetrahydroquinazolin-4-yl)-3-phenylthiourea (CAS 446277-61-8) is a high-purity analytical reference standard with the molecular formula C15H17N5S and a molecular weight of 299.39 g/mol.
The molecular framework of 1-(2-Amino-5,6,7,8-tetrahydroquinazolin-4-yl)-3-phenylthiourea (C15H17N5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Amino-5,6,7,8-tetrahydroquinazolin-4-yl)-3-phenylthiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17N5S |
| Molecular Weight | 299.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Amino Standards
- (S)-2-Amino-3,3-dimethyl-N-(3-sulfamoylbenzyl)butanamide (CAS 1185897-97-5)
- 2-{4-[3-Amino-4-(methylsulfonyl)phenyl]-1-piperazinyl}-1-ethanol (CAS 1219957-14-8)
- 4-Amino-2-methoxy-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide (CAS 62564-06-1)
- 4-Amino-n-[3-(morpholin-4-yl)propyl]benzene-1-sulfonamide (CAS 77837-45-7)
- 2-Amino-5-ethyl-4,6-diphenylnicotinonitrile (CAS 331979-90-9)
- 3-(4-Amino-5-mercapto-4H-[1,2,4]triazol-3-yl)-N,N-dimethyl-benzenesulfonamide (CAS 571154-99-9)
- (S)-2-Amino-1-{4-[(benzyl-isopropyl-amino)-methyl]-piperidin-1-yl}-3-methyl-butan-1-one (CAS 1353992-70-7)
- [1-((S)-2-Amino-propionyl)-piperidin-4-yl]-ethyl-carbamic acid tert-butyl ester (CAS 1354003-03-4)
Recommended Standards
- 1-(1-Ethyl-1H-indol-3-yl)-3-(thiophen-2-ylmethyl)urea (CAS 899990-81-9)
- 2-((1-(2-Oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indol-3-yl)thio)acetonitrile (CAS 895799-88-9)
- (S)-3-(((9H-Fluoren-9-yl)methyl)thio)-2-aminopropanoic acid (CAS 257288-48-5)
- 2-((5-(3,4-Dimethylphenyl)thieno[2,3-d]pyrimidin-4-yl)amino)ethan-1-ol (CAS 670270-70-9)
- 3-(Pyrrolidine-2-carboxamido)benzoic acid (CAS 1291160-19-4)
- 1-Methyl-5-(6-oxo-4-(trifluoromethyl)pyrimidin-1(6H)-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1823187-95-6)
- Sodium Hexanoate-6,6,6-d3 (CAS 1219794-91-8)
- S-(2-(3-((2R)-4-(((((((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)-2-hydroxy-3,3-dimethylbutanamido)propanamido)ethyl) octanethioate (CAS 1264-52-4)
- (4-Methyl-3-(3-(piperazin-1-yl)propoxy)phenyl)boronic acid (CAS 1704064-32-3)
- 2-Amino-N-(4-methoxycyclohexyl)acetamide (CAS 1353959-28-0)
- 5-(6-(Benzyloxy)-3-isopropyl-1H-indazol-5-yl)-4-(4-bromophenyl)-N-isopropyl-4H-1,2,4-triazole-3-carboxamide (CAS 1464091-41-5)
- 2-ethynyl-5-methyl-thiophene (CAS 81294-10-2)
- 5-Dodecylpyrimidine-2,4,6-triamine (CAS 94087-76-0)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com