2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid CAS 446829-82-9
| CAS No. | 446829-82-9 |
| Molecular Formula | C7H5N3O3S |
| Molecular Weight | 211.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid (CAS 446829-82-9), a certified reference material (molecular formula C7H5N3O3S, MW 211.20 g/mol) for analytical method development and quality control.
2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid (C7H5N3O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5N3O3S |
| Molecular Weight | 211.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- 2-Amino-6-nitrobenzo[d]thiazol-4-ol (CAS 460044-83-1)
- 3-Amino-1,1,1-trifluoro-2-(thiophen-2-yl)propan-2-ol (CAS 933721-59-6)
- 2-Amino-4-oxo-1,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 873544-81-1)
- Diethyl 3-(N-Hydroxyamino)propylphosphate (CAS 66508-19-8)
- Chlorinated paraffins (Cl: 38 % from NMR), technical mix (CAS 61788-76-9)
- 5-(Thiophen-2-ylsulfonyl)-8-(trifluoromethyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one (CAS 866138-35-4)
- 3-Chloro-2-iodoanisole (CAS 791642-67-6)
- 1-(Pyridin-4-ylmethyl)-1H-indazole-3-carboxylic acid (CAS 920019-75-6)
- 1-(2-Cyanophenyl)-N-cyclopropylmethanesulfonamide (CAS 1040339-14-7)
- (S)-2-amino-6-(benzyloxy)hexanoic acid (CAS 625845-34-3)
- 4-(3-Cyanophenyl)phenylacetic acid (CAS 893640-23-8)
- 3-(Pyrimidin-2-yl)benzenesulfonyl chloride (CAS 915707-50-5)
- 6,7-Dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine (CAS 199277-87-7)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
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