2-(2-Bromopyridin-4-yl)-1-(pyridin-2-yl)ethanone CAS 446852-65-9
| CAS No. | 446852-65-9 |
| Molecular Formula | C12H9BrN2O |
| Molecular Weight | 277.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-(2-Bromopyridin-4-yl)-1-(pyridin-2-yl)ethanone (CAS 446852-65-9), a certified reference material (molecular formula C12H9BrN2O, MW 277.12 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 2-(2-Bromopyridin-4-yl)-1-(pyridin-2-yl)ethanone is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 277.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H9BrN2O |
| Molecular Weight | 277.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromopyridin Standards
- n-(6-Bromopyridin-2-yl)benzamide (CAS 1153903-18-4)
- N-(4-Bromopyridin-2-yl)benzamide (CAS 1197371-39-3)
- N-(5-Bromopyridin-3-yl)benzamide (CAS 15862-47-2)
- N-(3-Bromopyridin-2-yl)benzamide (CAS 620939-76-6)
- N-(5-bromopyridin-2-yl)benzamide (CAS 62802-75-9)
- N-(5-bromopyridin-3-yl)cyclopropanesulfonamide (CAS 1083326-19-5)
- 2-(4-Bromopyridin-2-yl)isothiazolidine 1,1-dioxide (CAS 1597022-64-4)
- 3-(6-Bromopyridin-2-yl)-5-fluorobenzonitrile (CAS 1501214-05-6)
Recommended Standards
- 2-(2-(4-Bromophenyl)-5-methyloxazol-4-yl)acetonitrile (CAS 328918-83-8)
- 2-(4-Bromophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile (CAS 478081-43-5)
- 2-((5-Bromo-2-methylquinolin-8-yl)oxy)acetonitrile (CAS 88757-46-4)
- 2-(5-Bromofuran-2-yl)-1-methyl-1H-benzo[d]imidazole (CAS 33598-53-7)
- 3’-Chloro-2’-methylacetophenone (CAS 177942-43-7)
- 1-Methyl-3-(4-phenoxyphenyl)-2-thioxoimidazolidin-4-one (CAS 854137-28-3)
- 4-{2-[(3-Chloro[1,1-biphenyl]-4-yl)oxy]-ethyl}piperidine hydrochloride (CAS 1220030-03-4)
- 2,2,2-Trifluoro-N-(4-(2,2,2-trifluoroacetyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-5-yl)acetamide (CAS 1794736-68-7)
- N-(4-(Benzylamino)phenyl)acetamide (CAS 110137-65-0)
- 3-Chloro-3-morpholinomethyl benzophenone (CAS 898765-41-8)
- 1,2,3,4-Tetrahydropyrido[3,4-d]pyridazine (CAS 161034-61-3)
- methyl 3-(phenylthio)-1H-indole-2-carboxylate (CAS 116757-24-5)
- 4-Chloropicolinimidamide (CAS 760173-28-2)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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