2-Hydroxy-2-(4-phenoxyphenyl)acetic acid CAS 447-45-0
| CAS No. | 447-45-0 |
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Hydroxy-2-(4-phenoxyphenyl)acetic acid (CAS 447-45-0), molecular formula C14H12O4 and molecular weight 244.24 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Hydroxy-2-(4-phenoxyphenyl)acetic acid (C14H12O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 244.24 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Hydroxy-2-(4-phenoxyphenyl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Hydroxy Standards
- Phenyl 2-hydroxy-5-methoxybenzoate (CAS 10268-66-3)
- 4'-Hydroxy-5-methoxy-[1,1'-biphenyl]-2-carboxylic acid (CAS 1181608-93-4)
- 3'-Hydroxy-5'-methoxybiphenyl-3-carboxylic acid (CAS 1215205-51-8)
- 2'-Hydroxy-5'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1215206-03-3)
- 2-Hydroxy-4-methoxybiphenyl-3-carboxylic acid (CAS 1215206-20-4)
- 4'-Hydroxy-3'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1215206-61-3)
- 3'-Hydroxy-4'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1215206-75-9)
- 5-Hydroxy-3'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261903-47-2)
Recommended Standards
- 2-{[2-(Methoxycarbonyl)hydrazino]carbonyl}cyclohexanecarboxylic acid (CAS 899017-22-2)
- 2-Hydroxyphenyl 3-methoxybenzoate (CAS 5876-99-3)
- 2,8-Difluoro-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one (CAS 860625-65-6)
- 2-Mercapto-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile (CAS 893757-46-5)
- 1-(But-3-yn-1-yl)-1H-imidazole (CAS 911398-07-7)
- 1-(Isoquinolin-4-yl)-2-methylpropan-1-ol (CAS 27302-05-2)
- 2-Ethyl 5-methyl 7-hydroxybenzo[d][1,3]dioxole-2,5-dicarboxylate (CAS 1956328-23-6)
- (3-(3-Chloropropoxy)-4-methylphenyl)boronic acid (CAS 1704066-88-5)
- N-Acetyl-L-serine D3 (CAS 2230887-17-7)
- 4-(4-Pyridyl)cyclohexanone (CAS 103319-02-4)
- 3-(Phenylthio)-N-propylpropanamide (CAS 728932-74-9)
- 2,5,8,11,14,17,20,23,26,29-Decaoxadotriacontane-32-thiol (CAS 670234-58-9)
- Ethyl 2-amino-4-(4-isobutylphenyl)-5-methylthiophene-3-carboxylate (CAS 350990-25-9)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
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