4,9-Epoxynaphtho[2,3-c]furan-1,3-dione CAS 4480-96-0
| CAS No. | 4480-96-0 |
| Molecular Formula | C12H4O4 |
| Molecular Weight | 212.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 212.16 g/mol gives 4,9-Epoxynaphtho[2,3-c]furan-1,3-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4,9-Epoxynaphtho[2,3-c]furan-1,3-dione (CAS 4480-96-0), molecular formula C12H4O4 and molecular weight 212.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4,9-Epoxynaphtho[2,3-c]furan-1,3-dione (C12H4O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H4O4 |
| Molecular Weight | 212.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Epoxynaphtho Standards
Recommended Standards
- 4,6-Dimethyl-5-nitro-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 89977-22-0)
- 4-amino-2-methoxy-5-nitrobenzoate (CAS 59338-90-8)
- 3,4-Dimethyl-2,6-dinitrophenol (CAS 4097-61-4)
- 4-Hydroxy-5-methoxyisophthalic acid (CAS 2134-91-0)
- (2-Fluoro-4-iodo-3-methylphenyl)methanol (CAS 2386943-84-4)
- 4-Methylcyclohexylacetic Acid (CAS 6603-71-0)
- 4-Iodo-2,3-dihydro-1H-indole hydrochloride (CAS 1187929-37-8)
- 3-(1,2,2-Triphenylvinyl)benzaldehyde (CAS 2138330-46-6)
- (S)-2-((tert-Butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid (CAS 477254-82-3)
- Methyl 3-(2-phenylhydrazono)butanoate (CAS 2569-45-1)
- 1-(1-Ethoxycycloheptyl)-N-methylmethanamine (CAS 1249133-31-0)
- 4-(2-Naphthyl)-1,3-dithiol-2-thione (CAS 127198-67-8)
- 1-Oxo-1,2-dihydroisoquinoline-6-carbonitrile (CAS 1184916-94-6)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com