Methyl 3-((tert-butyldimethylsilyl)oxy)propanoate CAS 448944-56-7

Purity 97%+In StockPharmaceutical Standards
CAS No.448944-56-7
Molecular FormulaC10H22O3Si
Molecular Weight218.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 3-((tert-butyldimethylsilyl)oxy)propanoate CAS 448944-56-7 chemical structure

Description

The molecular framework of Methyl 3-((tert-butyldimethylsilyl)oxy)propanoate (C10H22O3Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies Methyl 3-((tert-butyldimethylsilyl)oxy)propanoate (CAS 448944-56-7), a certified reference material (molecular formula C10H22O3Si, MW 218.37 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 3-((tert-butyldimethylsilyl)oxy)propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H22O3Si
Molecular Weight218.37 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)2025

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