N-(4-Chloro-2-methoxy-5-methylphenyl)-2,4,6-trimethylbenzamide CAS 449158-32-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-Chloro-2-methoxy-5-methylphenyl)-2,4,6-trimethylbenzamide.

N-(4-Chloro-2-methoxy-5-methylphenyl)-2,4,6-trimethylbenzamide (CAS 449158-32-1), molecular formula C18H20ClNO2 and molecular weight 317.81 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, N-(4-Chloro-2-methoxy-5-methylphenyl)-2,4,6-trimethylbenzamide (C18H20ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 317.81 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Chloro-2-methoxy-5-methylphenyl)-2,4,6-trimethylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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