4-(Benzyloxy)propiophenone CAS 4495-66-3
| CAS No. | 4495-66-3 |
| Molecular Formula | C16H16O2 |
| Molecular Weight | 240.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Benzyloxy)propiophenone (C16H16O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-(Benzyloxy)propiophenone (CAS 4495-66-3) is a high-purity analytical reference standard with the molecular formula C16H16O2 and a molecular weight of 240.30 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Benzyloxy)propiophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16O2 |
| Molecular Weight | 240.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
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- 1-(2-(Benzyloxy)phenyl)propan-2-one (CAS 130936-16-2)
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- (E)-3-(3-(Benzyloxy)phenyl)prop-2-en-1-ol (CAS 155697-42-0)
- 2-Benzyloxy-4,5-dimethylbenzaldehyde (CAS 1809161-63-4)
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Recommended Standards
- 4,5-Methanochrysene (CAS 202-98-2)
- 4-Amino-N-(1-phenylethyl)benzamide (CAS 85592-75-2)
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- 4-Amino-N-(2,3-dimethylphenyl)benzamide (CAS 29027-72-3)
- 5-Bromo-8-chloro-2-hydroxyquinolin-4(1H)-one (CAS 1996052-61-9)
- 3-(1-methyl-1H-pyrazol-4-yl)butanoic acid (CAS 1540383-56-9)
- 3-Phenyl-4-(1H-tetrazol-5-ylcarbamoyl)-butyric acid 3-phenyl-4-(1 h-tetrazol-5-ylcarbamoyl)-butyric acid 3-phenyl-4-(1h-tetrazol-5-ylcarbamoyl)butyric acid 428504-04-5 (CAS 428504-04-5)
- 4-(2-Chloropyrido[2,3-d]pyrimidin-4-yl)morpholine (CAS 908142-01-8)
- (1S,2S)-rel-2-(6-Bromopyridin-3-yl)cyclopropane-1-carboxylic acid (CAS 918305-72-3)
- 2-Chloro-1-(1-tosyl-1h-pyrrol-3-yl)ethan-1-one (CAS 124511-96-2)
- 3-Cyclopropoxy-4-isopropylbenzaldehyde (CAS 1243408-57-2)
- (S)-1-(3-(benzyloxy)phenyl)-3-(dimethylamino)-2-methylpropan-1-one (2R,3R)-2,3-bis(benzoyloxy)succinate (CAS 1004315-81-4)
- 2-Pentyl isothiocyanate (CAS 201224-94-4)
- Peptide Impurity 34 (CAS 21282-09-7)
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