4-(Benzyloxy)phenyl di(aziridin-1-yl)phosphinate CAS 4497-73-8
| CAS No. | 4497-73-8 |
| Molecular Formula | C18H12ClNO3 |
| Molecular Weight | 325.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Benzyloxy)phenyl di(aziridin-1-yl)phosphinate.
4-(Benzyloxy)phenyl di(aziridin-1-yl)phosphinate (CAS 4497-73-8) is a high-purity analytical reference standard with the molecular formula C18H12ClNO3 and a molecular weight of 325.75 g/mol.
The molecular framework of 4-(Benzyloxy)phenyl di(aziridin-1-yl)phosphinate (C18H12ClNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12ClNO3 |
| Molecular Weight | 325.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Benzyloxy Standards
- 4-Acetyl-6-(benzyloxy)pyridine-2-sulfonyl chloride (CAS 1393531-27-5)
- 2-Acetyl-6-(benzyloxy)pyridine-4-sulfonyl chloride (CAS 1393551-20-6)
- 2-(Benzyloxy)-5-bromobenzoyl chloride (CAS 1160249-51-3)
- 3-(Benzyloxy)-6-bromo-2-chlorobenzaldehyde (CAS 2404734-00-3)
- N-{3-[4-(benzyloxy)phenoxy]propyl}cyclopentanamine (CAS 1002513-89-4)
- 3-[3-(Benzyloxy)pyridin-2-yl]-1-cyclohexylurea (CAS 1024353-45-4)
- 2-[3-(Benzyloxy)phenyl-4-methoxy-]-1-(1-pyrrolidinyl)ethanone (CAS 1206614-03-0)
- 2-(4-(Benzyloxy)phenyl)-1-(3-methoxypyrrolidin-1-yl)ethanone (CAS 1391054-62-8)
Recommended Standards
- 3-Chloro-4-(4-nitrophenoxy)-1,1'-biphenyl (CAS 6945-85-3)
- 4-Chloro-N-(2-oxo-6-phenyl-2H-pyran-3-yl)benzamide (CAS 478043-23-1)
- 1-(4-Chlorophenyl)-4-oxo-N-phenyl-1,4-dihydropyridazine-3-carboxamide (CAS 478063-44-4)
- 5'-Chloro-5'-deoxy-2',3'-O-isopropylideneadenosine (CAS 24514-56-5)
- (E)-{1-[4-(1H-imidazol-1-yl)phenyl]ethylidene}amino N-phenylcarbamate (CAS 477850-31-0)
- Diindeno[7,1-qr:1′,7′-st][1,4,7,10,13,16]hexaoxacycloheneicosin, 5,6,8,9,11,12,14,15,17,18,23,24,25,26-tetradecahydro-, (24aR)- (CAS 879014-42-3)
- 2-Acetyl-3-hydroxyisonicotinic acid (CAS 1393561-62-0)
- (R)-1-(3-(Trifluoromethoxy)phenyl)ethanamine (CAS 1228559-55-4)
- Lesinurad (CAS 878672-00-5)
- (S)-(+)-2,2''-Bis(diphenylphosphino)-1,1''-binaphthalene]chloro(benzene)ruthenium chloride (CAS 126251-92-1)
- Methyl (Z)-3-(3-bromo-1H-1,2,4-triazol-5-yl)acrylate (CAS 1365988-78-8)
- 2-Amino-4-chloro-6-methoxypyrimidine-5-carbonitrile (CAS 900456-49-7)
- 7-Chloro-5-methylindole, 97% (CAS 5147-22-8)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com