2-(Morpholin-4-yl)quinoline-4-carboxylic acid CAS 449764-66-3

Purity 97%+In StockPharmaceutical Standards
CAS No.449764-66-3
Molecular FormulaC14H14N2O3
Molecular Weight258.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Morpholin-4-yl)quinoline-4-carboxylic acid CAS 449764-66-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Morpholin-4-yl)quinoline-4-carboxylic acid.

2-(Morpholin-4-yl)quinoline-4-carboxylic acid (CAS 449764-66-3) is a high-purity analytical reference standard with the molecular formula C14H14N2O3 and a molecular weight of 258.27 g/mol.

2-(Morpholin-4-yl)quinoline-4-carboxylic acid (C14H14N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Morpholin-4-yl)quinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H14N2O3
Molecular Weight258.27 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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