4-Chloro-2-(3-chlorophenyl)-5-(piperazin-1-yl)pyridazin-3(2H)-one CAS 449778-66-9
| CAS No. | 449778-66-9 |
| Molecular Formula | C14H14Cl2N4O |
| Molecular Weight | 325.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-2-(3-chlorophenyl)-5-(piperazin-1-yl)pyridazin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Chloro-2-(3-chlorophenyl)-5-(piperazin-1-yl)pyridazin-3(2H)-one (CAS 449778-66-9) is a high-purity analytical reference standard with the molecular formula C14H14Cl2N4O and a molecular weight of 325.19 g/mol.
The molecular framework of 4-Chloro-2-(3-chlorophenyl)-5-(piperazin-1-yl)pyridazin-3(2H)-one (C14H14Cl2N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14Cl2N4O |
| Molecular Weight | 325.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
- 4-[(3,4-Dichlorobenzyl)oxy]-3-ethoxybenzaldehyde (CAS 423148-76-9)
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- Ethyl 4-(benzyloxy)-3,5-dichlorobenzoate (CAS 40689-39-2)
- 4-[(2,4-Dichlorobenzyl)oxy]-3-ethoxybenzaldehyde (CAS 331464-01-8)
- 5-Azaindole (CAS 271-34-1)
- 2-(4-(2,4-Dichlorophenyl)thiazol-2-yl)-3-((2,4-difluorophenyl)amino)acrylonitrile (CAS 799770-31-3)
- 7-Bromo-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione (CAS 1447671-23-9)
- (5-Methoxybenzo[c][1,2,5]thiadiazol-4-yl)methanamine (CAS 744157-61-7)
- 4-(2-Methoxyphenyl)-6-(4-methylpiperazino)-2-phenyl-5-pyrimidinecarbonitrile (CAS 477853-98-8)
- 4-Cyclopropoxy-3-(methylsulfonamido)benzenesulfonamide (CAS 1243349-77-0)
- 2-(1-Methyl-1h-pyrazol-4-yl)cyclopentan-1-ol (CAS 1247509-99-4)
- [(3S)-1-methylpyrrolidin-3-yl]methanol (CAS 1210934-04-5)
- 3-Amino-6-ethyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 1206969-66-5)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
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