4-Fluoro-2-methoxyaniline CAS 450-91-9
| CAS No. | 450-91-9 |
| Molecular Formula | C7H8FNO |
| Molecular Weight | 141.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Fluoro-2-methoxyaniline (CAS 450-91-9), a certified reference material (molecular formula C7H8FNO, MW 141.14 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-2-methoxyaniline (C7H8FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8FNO |
| Molecular Weight | 141.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- 3-Fluoro-6-methoxy-2-methylpyridine (CAS 375368-86-8)
- 4-(Aminomethyl)-2-fluorophenol (CAS 771581-11-4)
- 3-Fluoro-5-methoxyaniline (CAS 2339-58-4)
- 4-(Aminomethyl)-3-fluorophenol (CAS 754971-62-5)
- 2-Amino-5-oxo-4-(p-tolyl)-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 326915-49-5)
- 4-Chloro-|A-methyl-benzenemethanamine; 4-Chloro-|A-methylbenzylamine 6299-02-1 AB1008303 (CAS 6299-02-1)
- N-[(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide (CAS 54879-64-0)
- 4-(Azetidin-3-yl)-2-(trifluoromethyl)pyridine (CAS 2159739-48-5)
- 1-(6-Methylpyrimidin-4-yl)cyclopropanol (CAS 116186-31-3)
- 3-(3,5-Dichlorophenoxy)azetidine (CAS 1339830-61-3)
- 1H-Pyrazolo[4,3-b]pyridine, 6-[2-(2-chloro-5-pyrimidinyl)ethynyl]-1-methyl- (CAS 2539141-17-6)
- (2S,3R,4S,5R,6R)-2-methoxy-6-methyltetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 19940-17-1)
- 2-Propenoic acid, butyl ester, polymer with 1,1-dichloroethene (CAS 9011-09-0)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
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