2,4-Dichloro-N-(4-(piperidin-1-yl)phenyl)benzamide CAS 450364-75-7

Purity 97%+In StockPharmaceutical Standards
CAS No.450364-75-7
Molecular FormulaC18H18Cl2N2O
Molecular Weight349.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,4-Dichloro-N-(4-(piperidin-1-yl)phenyl)benzamide CAS 450364-75-7 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2,4-Dichloro-N-(4-(piperidin-1-yl)phenyl)benzamide (CAS 450364-75-7), molecular formula C18H18Cl2N2O and molecular weight 349.25 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,4-Dichloro-N-(4-(piperidin-1-yl)phenyl)benzamide (C18H18Cl2N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), 2,4-Dichloro-N-(4-(piperidin-1-yl)phenyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H18Cl2N2O
Molecular Weight349.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2

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