2-Chloro-5-(methylsulfonamido)benzoic acid CAS 450368-37-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-(methylsulfonamido)benzoic acid.

2-Chloro-5-(methylsulfonamido)benzoic acid (CAS 450368-37-3) is a high-purity analytical reference standard with the molecular formula C8H8ClNO4S and a molecular weight of 249.67 g/mol.

The molecular framework of 2-Chloro-5-(methylsulfonamido)benzoic acid (C8H8ClNO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-5-(methylsulfonamido)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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