5-Bromo-2-iodo-1,1'-biphenyl CAS 4510-78-5
| CAS No. | 4510-78-5 |
| Molecular Formula | C12H8BrI |
| Molecular Weight | 359.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-2-iodo-1,1'-biphenyl is closely related to bromine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-2-iodo-1,1'-biphenyl (CAS 4510-78-5), molecular formula C12H8BrI and molecular weight 359.00 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-iodo-1,1'-biphenyl (C12H8BrI) is characterized by bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-iodo-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8BrI |
| Molecular Weight | 359.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br/I-containing |
Related Bromo Standards
- 4-Bromo-4'-iodobiphenyl (CAS 105946-82-5)
- 2-Bromo-5-iodo-1,1'-biphenyl (CAS 1226452-23-8)
- 4’-Bromo-3-iodo-1,1’-biphenyl (CAS 130201-21-7)
- 3-Bromo-5-iodo-1,1'-biphenyl (CAS 136649-44-0)
- 3′-Bromo-4-Iodo-Biphenyl (CAS 187275-73-6)
- 3-Bromo-3'-iodo-1,1'-biphenyl (CAS 187275-76-9)
- 2-Bromo-2'-iodo-1,1'-biphenyl (CAS 39655-12-4)
- 3-Bromo-4-iodobiphenyl (CAS 900806-53-3)
Recommended Standards
- 5-Bromo-6-iodo-1,2-dihydroacenaphthylene (CAS 55157-87-4)
- Methyl 2-bromo-4-fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2377607-39-9)
- Methyl 2-bromo-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2096331-46-1)
- Methyl 2-bromo-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2788844-14-2)
- 2-Amino-3-bromo-5-phenylpyridine (CAS 107351-80-4)
- 1-(4-(4-Chlorophenyl)thiazol-2-yl)guanidine (CAS 7120-02-7)
- Tert-butyl 4-amino-2-phenylpyrrolidine-1-carboxylate (CAS 1554371-70-8)
- (S)-3-((tert-Butoxycarbonyl)amino)-3-(3-chlorophenyl)propanoic acid (CAS 500770-74-1)
- 4,4,6,8,9-Pentamethyl-4H-pyrrolo[3,2,1-ij]-quinoline-1,2-dione (CAS 488734-86-7)
- 3-((4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)methyl)benzonitrile (CAS 1016690-59-7)
- Cyromazine Impurity 1 (CAS 66215-24-5)
- 1-(2,4-Dichlorophenyl)-N,5-dimethyl-1H-1,2,4-triazole-3-carboxamide (CAS 338398-17-7)
- 2-(5-Amino-benzoimidazol-1-yl)-ethanoldihydrochloride (CAS 1158248-63-5)
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