(3,5-Difluoro-benzyl)-phosphonic acid diethyl ester CAS 451455-96-2
| CAS No. | 451455-96-2 |
| Molecular Formula | C11H15F2O3P |
| Molecular Weight | 264.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3,5-Difluoro-benzyl)-phosphonic acid diethyl ester is closely related to a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3,5-Difluoro-benzyl)-phosphonic acid diethyl ester (CAS 451455-96-2), molecular formula C11H15F2O3P and molecular weight 264.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (3,5-Difluoro-benzyl)-phosphonic acid diethyl ester is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 264.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3,5-Difluoro-benzyl)-phosphonic acid diethyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15F2O3P |
| Molecular Weight | 264.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
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- 85J5ZP6YSL 190977-41-4 Oblimersen sodium [USAN] DNA, d(P-thio)(T-C-T-C-C-C-A-G-C-G-T-G-C-G-C-C-A-T) P-Thiothymidylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-P-thiothymidylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thioadenylyl-(3'to 5')-2'-deoxy-P-thioguanylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thioguanylyl-(3'to 5')-P-thiothymidylyl-(3'to 5')-2'-deoxy-P-thioguanylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thioguanylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-2'-deoxy-P-thioadenylyl-(3'to 5')-thymidine heptadecasodium salt Augmerosen G 3139 Oblimersen sodium Genasense D-G3139 Oblimersen G3139 UNII-85J5ZP6YSL (CAS 190977-41-4)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
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