1-(3,4-Dichlorobenzyl)piperidine-4-carboxylic acid hydrochloride CAS 451485-54-4
| CAS No. | 451485-54-4 |
| Molecular Formula | C13H15Cl2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(3,4-Dichlorobenzyl)piperidine-4-carboxylic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(3,4-Dichlorobenzyl)piperidine-4-carboxylic acid hydrochloride (CAS 451485-54-4) is a high-purity analytical reference standard with the molecular formula C13H15Cl2NO2HCl and a molecular weight of 324.63 g/mol.
1-(3,4-Dichlorobenzyl)piperidine-4-carboxylic acid hydrochloride (C13H15Cl2NO2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H15Cl2NO2 HCl |
| Molecular Weight | 324.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichlorobenzyl Standards
- 5-(2,6-Dichlorobenzyl)pyrimidine-2,4-diamine (CAS 1000575-30-3)
- 1-(2,6-Dichlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001510-39-9)
- 1-(2,6-Dichlorobenzyl)-3-isothiocyanato-1h-pyrazole (CAS 1004193-34-3)
- 1-(2,6-Dichlorobenzyl)-4-isothiocyanato-1h-pyrazole (CAS 1004193-55-8)
- 1-(2,4-Dichlorobenzyl)-4-isothiocyanato-1h-pyrazole (CAS 1004193-57-0)
- 1-(3,4-Dichlorobenzyl)cyclopropan-1-amine (CAS 1004284-66-5)
- 4-(1-(2,4-Dichlorobenzyl)-3,5-dimethyl-1h-pyrazol-4-yl)-5-ethyl-4h-1,2,4-triazole-3-thiol (CAS 1006358-33-3)
- 3-(1-(2,6-Dichlorobenzyl)-3,5-dimethyl-1h-pyrazol-4-yl)acrylic acid (CAS 1006441-70-8)
Recommended Standards
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- 2-(5-cyano-1-methyl-1H-pyrrol-2-yl)acetic acid (CAS 71290-65-8)
- 7,8-Dihydroindolo[2',3':3,4]pyrido[1,2-b][2,7]naphthyridin-5(13H)-one (CAS 57103-51-2)
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- Etrasimod impurity 18 (CAS CATO-C4X-321418)
- 3-Phenyl-4-({[4-(trifluoromethoxy)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338394-42-6)
- N-(5-Amino-2-methoxyphenyl)-4-ethoxybenzamide (CAS 1016534-44-3)
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