4-Chloro-2-fluoro-1-methoxybenzene CAS 452-09-5
| CAS No. | 452-09-5 |
| Molecular Formula | C7H6ClFO |
| Molecular Weight | 160.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Chloro-2-fluoro-1-methoxybenzene (CAS 452-09-5), a certified reference material (molecular formula C7H6ClFO, MW 160.57 g/mol) for analytical method development and quality control.
Based on its molecular formula C7H6ClFO, 4-Chloro-2-fluoro-1-methoxybenzene contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 160.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Chloro-2-fluoro-1-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClFO |
| Molecular Weight | 160.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-1-fluoro-2-methoxybenzene (CAS 1092349-89-7)
- 2-Chloro-4-fluoro-3-methylphenol (CAS 1232693-41-2)
- 4-Chloro-2-fluoro-3-methylphenol (CAS 1351668-24-0)
- 3-Chloro-4-fluorobenzyl Alcohol (CAS 161446-90-8)
- 5-CHloro-2-fluoro-3-methylphenol (CAS 1781655-28-4)
- 3-Chloro-4-fluoro-5-methylphenol (CAS 1784533-88-5)
- 2-chloro-5-fluoro-4-methylphenol (CAS 1803588-57-9)
- 2-Chloro-4-fluoro-6-methylphenol (CAS 1804404-41-8)
Recommended Standards
- 3-Chloro-5-fluorobenzyl Alcohol (CAS 79944-64-2)
- 4-Chloro-2-fluorobenzyl Alcohol (CAS 56456-49-6)
- 3-CHLORO-5-FLUOROANISOLE (CAS 202925-08-4)
- 4-Chloro-3-fluoroanisole (CAS 501-29-1)
- LY 364947 (CAS 396129-53-6)
- Potassium Propionate (CAS 327-62-8)
- tert-Butyl 2-(6-amino-2-methylpyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352486-99-7)
- (2S,4R)-N,N-Dibenzyl-4-hydroxypyrrolidine-2-carboxamide (CAS 915205-76-4)
- 3-Bromo-2,5-difluoroaniline hydrochloride (CAS 1787929-07-0)
- Calcium Thioglycolate Trihydrate (CAS 5793-98-6)
- 3,5-Difluoro-4-(4-fluorophenoxy)aniline (CAS 549547-31-1)
- 5-(Chloromethyl)-2-cyclopropylthiazole (CAS 1468426-47-2)
- 2-(2-Chloro-4-(trifluoromethyl)phenoxy)aniline (CAS 98968-75-3)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
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