Selegiline EP Impurity E HCl CAS 4528-52-3
| CAS No. | 4528-52-3 |
| Molecular Formula | C13H17N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Selegiline EP Impurity E HCl is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 223.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Selegiline EP Impurity E HCl (CAS 4528-52-3, C13H17NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Selegiline EP Impurity E HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H17N HCl |
| Molecular Weight | 223.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Selegiline Standards
- Selegiline EP Impurity D HCl (CAS 115586-38-4)
- Selegiline-D5 Hydrochloride (CAS 1217705-21-9)
- (RS)-Selegiline hydrochloride CRS (CAS 14611-51-9)
- Selegiline Hydrochloride (CAS 14611-52-0)
- Selegiline Hydrochloride EP Impurity D (CAS 2588-96-7)
- Selegiline EP Impurity E (CAS 4528-51-2)
- Selegiline EP Impurity D (CAS 56862-28-3)
- Selegiline EP Impurity C (CAS 73917-84-7)
Recommended Standards
- Orforglipron impurity 24 (CAS CATO-C4X-323424)
- Urapidil Impurity 47 (CAS CATO-C4X-192447)
- Propetamphos Impurity 1 (CAS 99606-11-8)
- N-(5-(Benzo[d][1,3]dioxol-5-yl)-1,3,4-oxadiazol-2-yl)cyclopropanecarboxamide (CAS 922018-23-3)
- (5-Formyl-2-methylphenyl)boronic acid (CAS 1186398-35-5)
- N-(4-(4-(2-Ethoxyphenyl)-5-mercapto-4H-1,2,4-triazol-3-yl)phenyl)methanesulfonamide (CAS 917747-31-0)
- (2-Phenylethyl)(prop-2-en-1-yl)amine (CAS 5263-58-1)
- Methyl 2-bromo-4-methylbenzo[d]thiazole-6-carboxylate (CAS 1190311-43-3)
- N-Benzylpentan-2-amine hydrochloride (CAS 2103392-27-2)
- Peptide 437 (CAS CATO-CPTD788437)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com