3-Bromo-5-(4-methoxyphenyl)pyridine CAS 452972-07-5
| CAS No. | 452972-07-5 |
| Molecular Formula | C12H10BrNO |
| Molecular Weight | 264.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Bromo-5-(4-methoxyphenyl)pyridine (C12H10BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 3-Bromo-5-(4-methoxyphenyl)pyridine (CAS 452972-07-5), a certified reference material (molecular formula C12H10BrNO, MW 264.12 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10BrNO |
| Molecular Weight | 264.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-N-(pyridin-3-ylmethyl)pyridin-2(1h)-imine (CAS 1036505-24-4)
- 5-Bromo-N-(pyridin-4-ylmethyl)pyridin-2-amine (CAS 1040008-79-4)
- 5-Bromo-N-(pyridin-2-ylmethyl)pyridin-2-amine (CAS 1041542-35-1)
- 5-Bromo-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 1100345-72-9)
- 5-Bromo-2-(3-methoxyphenyl)pyridine (CAS 1119089-23-4)
- 2-Bromo-N-(naphthalen-1-yl)acetamide (CAS 1136-82-9)
- N-(5-Bromo-2-fluorophenyl)hydrazinecarbothioamide (CAS 1153254-46-6)
- 3-Bromo-4-phenoxyaniline, 97% (CAS 1159607-48-3)
Recommended Standards
- 3-Bromo-5-(3-methoxyphenyl)pyridine (CAS 675590-10-0)
- 3-Bromo-5-(m-tolyloxy)pyridine (CAS 28231-75-6)
- 3-Bromo-4-(4-methoxyphenyl)pyridine (CAS 88345-97-5)
- 4-(2-Bromophenoxy)aniline (CAS 57688-14-9)
- 2-(3,4-Dichlorophenyl)-2-oxoacetaldehyde hydrate (CAS 859775-23-8)
- 3-(4-(2-(Methylthio)acetamido)phenyl)acrylic acid (CAS 1050142-66-9)
- 2-(Pyridin-4-yl)ethanethioamide (CAS 5451-38-7)
- 2-cyanopropanoic Acid (CAS 632-07-5)
- (R)-methyl 5-(6-(chloromethyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate (CAS 929095-40-9)
- Tert-butyl pentylglycinate (CAS 66116-17-4)
- 3-(4-Chloro-2-nitrophenoxy)propanoic acid (CAS 5791-14-0)
- [(4E)-6-Methyl-3,4-dihydro-2H-1-benzothiopyran-4-ylidene]amino 4-methylbenzoate (CAS 383145-43-5)
- N-Phenylmethanesulfonamide (CAS 1197-22-4)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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