5-Bromopyridine-3-boronic acid CAS 452972-09-7

Purity 97%+In StockPharmaceutical Standards
CAS No.452972-09-7
Molecular FormulaC5H5BBrNO2
Molecular Weight201.81 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromopyridine-3-boronic acid CAS 452972-09-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromopyridine-3-boronic acid.

CATO supplies 5-Bromopyridine-3-boronic acid (CAS 452972-09-7), a certified reference material (molecular formula C5H5BBrNO2, MW 201.81 g/mol) for analytical method development and quality control.

5-Bromopyridine-3-boronic acid (C5H5BBrNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H5BBrNO2
Molecular Weight201.81 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2025
Halogen ContentBr-containing
Nitrogen Atoms1

Related Bromopyridine Standards

Recommended Standards

Why CATO?