1,3-Difluoro-2-propanol (Stabilized with NaF) CAS 453-13-4
| CAS No. | 453-13-4 |
| Molecular Formula | C3H6F2O |
| Molecular Weight | 96.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-Difluoro-2-propanol (Stabilized with NaF).
1,3-Difluoro-2-propanol (Stabilized with NaF) (CAS 453-13-4) is a high-purity analytical reference standard with the molecular formula C3H6F2O and a molecular weight of 96.08 g/mol.
The molecular framework of 1,3-Difluoro-2-propanol (Stabilized with NaF) (C3H6F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,3-Difluoro-2-propanol (Stabilized with NaF) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H6F2O |
| Molecular Weight | 96.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Difluoro Standards
- (2,2-Difluoro-ethyl)-hydrazine (CAS 1039959-85-7)
- (2S)-1,1-Difluoro-2-propanol (CAS 948828-04-4)
- 1,1-Difluoro-2-propanol (CAS 431-04-9)
- 2,2-Difluoro-1-propanol (CAS 33420-52-9)
- 2,2-Difluoro-N-methylethanamine (CAS 60168-06-1)
- 1,1-Difluoro-1-butene (CAS 407-09-0)
- 2,5-Difluoro-1H-imidazole (CAS 89676-70-0)
- 1,1-Difluoro-3-Methylene-Cyclobutane (CAS 110654-33-6)
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