4,4,4-Trifluoro-3-hydroxybutanamide CAS 453-34-9
| CAS No. | 453-34-9 |
| Molecular Formula | C4H6F3NO2 |
| Molecular Weight | 157.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4,4-Trifluoro-3-hydroxybutanamide is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4,4,4-Trifluoro-3-hydroxybutanamide (CAS 453-34-9), a certified reference material (molecular formula C4H6F3NO2, MW 157.09 g/mol) for analytical method development and quality control.
The molecular framework of 4,4,4-Trifluoro-3-hydroxybutanamide (C4H6F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6F3NO2 |
| Molecular Weight | 157.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
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Recommended Standards
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- 1,2-Difluoro-5-methyl-3-nitrobenzene (CAS 468718-05-0)
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- Topicamide lmpurity 10 (CAS CATO-C4X-215010)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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