3895AE 453557-52-3 C12H11ClN2O2S N-{3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-phenyl}acetamide CAS 453557-52-3

Purity 97%+In StockPharmaceutical Standards
CAS No.453557-52-3
Molecular FormulaC12H11ClN2O2S
Molecular Weight282.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3895AE
453557-52-3
C12H11ClN2O2S
N-{3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-phenyl}acetamide CAS 453557-52-3 chemical structure

Description

The occurrence of 3895AE 453557-52-3 C12H11ClN2O2S N-{3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-phenyl}acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3895AE 453557-52-3 C12H11ClN2O2S N-{3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-phenyl}acetamide (CAS 453557-52-3), molecular formula C12H11ClN2O2S and molecular weight 282.75 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 3895AE 453557-52-3 C12H11ClN2O2S N-{3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-phenyl}acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H11ClN2O2S
Molecular Weight282.75 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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