N-(2-Fluoro-5-nitrophenyl)acetamide CAS 454-07-9
| CAS No. | 454-07-9 |
| Molecular Formula | C8H7FN2O3 |
| Molecular Weight | 198.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(2-Fluoro-5-nitrophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-(2-Fluoro-5-nitrophenyl)acetamide (CAS 454-07-9) is a high-purity analytical reference standard with the molecular formula C8H7FN2O3 and a molecular weight of 198.15 g/mol.
Based on its molecular formula C8H7FN2O3, N-(2-Fluoro-5-nitrophenyl)acetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 198.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7FN2O3 |
| Molecular Weight | 198.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 4-Fluoro-N-methyl-2-nitrobenzamide (CAS 1018983-85-1)
- 2-(5-Fluoro-2-methoxyphenyl)-2-oxoacetic acid (CAS 1094355-95-9)
- 4-Fluoro-2-trifluoromethylbenzo-6-d<SUB>1</SUB>-nitrile-<SUP>13</SUP>C,<SUP>15</SUP>N (CAS 1216879-97-8)
- N-(2-Fluoro-6-nitrophenyl)guanidine (CAS 1217015-88-7)
- 7-Fluoro-6-nitro-3,4-dihydro-2h-benzo[b][1,4]oxazine (CAS 122138-83-4)
- 3-Fluoro-n-methyl-5-nitrobenzamide (CAS 1239596-39-4)
- 3-Fluoro-2-(methoxycarbonyl)benzoic acid (CAS 1256593-37-9)
- 2-Fluoro-6-(methoxycarbonyl)benzoic acid (CAS 1256593-39-1)
Recommended Standards
- N-(2-fluoro-3-nitrophenyl)acetamide (CAS 521074-19-1)
- N-(2-fluoro-6-nitrophenyl)acetamide (CAS 342-52-9)
- Methyl 5-fluorobenzo[d][1,3]dioxole-4-carboxylate (CAS 492444-07-2)
- N-(3-fluoro-4-nitrophenyl)acetamide (CAS 345-30-2)
- Fosnetupitant (CAS 1703748-89-3)
- Benzofuran-7-ol (CAS 4790-81-2)
- 1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic acid (CAS 5932-32-1)
- n-{1-[(4-methylphenyl)methyl]-1,2-dihydropyridin-2-ylidene}-1h-indazole-3-carboxamide (CAS 1223877-09-5)
- methyl 3-iodopyridine-4-carboxylate (CAS 188677-49-8)
- 6-bromo-1H-pyrrolo[2,3-b]pyridine-3-sulfonic acid (CAS 2361020-98-4)
- Imrecoxib Impurity 23 (CAS CATO-C4X-237923)
- 4-((Methoxymethoxy)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 2568989-53-5)
- Triethyl 1-fluoro-2-hydroxypropane-1,2,3-tricarboxylate (CAS 309-98-8)
- Tirzepatide Impurity 25 X TFA Salt (CAS CATO-C4X-324025)
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