(1,4-Phenylenebis(methylene))diphosphonic acid CAS 4546-06-9
| CAS No. | 4546-06-9 |
| Molecular Formula | C8H12O6P2 |
| Molecular Weight | 266.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (1,4-Phenylenebis(methylene))diphosphonic acid (CAS 4546-06-9), a certified reference material (molecular formula C8H12O6P2, MW 266.12 g/mol) for analytical method development and quality control.
Owing to a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, (1,4-Phenylenebis(methylene))diphosphonic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 266.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures (1,4-Phenylenebis(methylene))diphosphonic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12O6P2 |
| Molecular Weight | 266.12 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
Related Phenylenebis Standards
- (1,3-Phenylenebis(methylene))diphosphonic acid (CAS 144052-40-4)
- (1,2-Phenylenebis(methylene))bis(phosphonic acid) (CAS 42104-58-5)
- 2,2'-(1,4-Phenylenebis(oxy))diacetyl chloride (CAS 1889-01-6)
- 5,5'-(1,4-Phenylenebis(oxy))dipentanenitrile (CAS 47096-71-9)
- 3,3'-(1,2-Phenylenebis(oxy))bis(propane-1,2-diol) (CAS 56266-47-8)
- 3,3-[1,3-Phenylenebis(oxy)]dipropanoic acid (CAS 61479-41-2)
- 3,3'-(1,4-Phenylenebis(oxy))bis(butan-2-one) (CAS 477865-72-8)
- 1,2-Phenylenebis(phenylmethanone) (CAS 1159-86-0)
Recommended Standards
- (2-Aminophenyl)(2,5-dichlorophenyl)methanone (CAS 21723-84-2)
- 5-Ethyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1905413-47-9)
- (4-Amino-2-chlorophenyl)(4-chlorophenyl)methanone (CAS 50274-85-6)
- 2-Cyclopropyl-6-(iodomethyl)tetrahydro-2H-pyran (CAS 1849204-12-1)
- 1-(5-Phenyl-1H-1,2,4-triazol-3-yl)urea (CAS 6642-32-6)
- (3-Bromophenyl)(3-(trifluoromethyl)phenyl)methanone (CAS 1220124-43-5)
- 3-Bromo-5-(oxetan-3-yl)pyridine (CAS 1404367-33-4)
- 2,4-Dimethyl-3-fluorobenzoic acid (CAS 26583-81-3)
- Azilsartan Impurity 171 (CAS CATO-C4X-1096171)
- (1S,2R,5S)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide (CAS 1383814-73-0)
- 1-(Ethoxycarbonyl)cyclopropane-1-sulfinate (sodium) (CAS 2917638-95-8)
- 2-Hydroxy-5-(3-nitrophenyl)pyridine (CAS 1111106-29-6)
- 3,4-Dichloro-2,2-dimethylbutyrophenone (CAS 898765-98-5)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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