1H-1,2,3-Triazole-4,5-dicarboxylic acid CAS 4546-95-6
| CAS No. | 4546-95-6 |
| Molecular Formula | C4H3N3O4 |
| Molecular Weight | 157.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1H-1,2,3-Triazole-4,5-dicarboxylic acid is closely related to a carbohydrate-derived structure, an amide group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1H-1,2,3-Triazole-4,5-dicarboxylic acid (CAS 4546-95-6), a certified reference material (molecular formula C4H3N3O4, MW 157.08 g/mol) for analytical method development and quality control.
1H-1,2,3-Triazole-4,5-dicarboxylic acid (C4H3N3O4) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H3N3O4 |
| Molecular Weight | 157.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
Related H Standards
- 1H-1,2,4-Triazole-3,5-dicarboxylic acid (CAS 34550-41-9)
- 2H-1,2,3-Triazole-4,5-dicarboxylic acid (CAS 294853-04-6)
- 3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-methyl-5-(1-methylethyl)- (9CI) 588680-36-8 (CAS 588680-36-8)
- Triazole alanine (CAS 114419-45-3)
- 1,2,3-Triazole-2-acetic acid ethyl ester, 97% (CAS 4320-90-5)
- 1H-1,2,3-Triazole-1-acetic acid, ethyl esterethyl 2-(1H-1,2,3-triazol-1-yl)acetate (CAS 4314-21-0)
- 1H-1,2,4-Triazole-3,5-dicarboxamide (CAS 111340-55-7)
- 2H-1,2,3-Triazole-4,5-dicarboxamide (CAS 388623-87-8)
Recommended Standards
- (4,5-Dioxo-4,5-dihydro-1H-pyrazol-3-yl)carbamic acid (CAS 859955-10-5)
- Isoxazole-3,4-dicarboxylic acid (CAS 15440-76-3)
- Oxazole-2,5-dicarboxylic acid (CAS 1449569-97-4)
- 2-Hydroxy-4-nitrofuran-3-carbaldehyde (CAS 263144-37-2)
- 5-Bromo-4-chloro-2-fluorobenzoic acid (CAS 289038-22-8)
- 4-Amino-N-(2-chlorophenyl)benzamide (CAS 888-79-9)
- (1-Bromocyclopentyl)(3-chlorophenyl)methanone (CAS 52123-79-2)
- 4-Fluoro-1h-spiro[benzo[c]isothiazole-3,4'-piperidine] 2,2-dioxide hydrochloride (CAS 2490698-20-7)
- n-((1h-Imidazol-2-yl)methyl)-2,5-difluoroaniline (CAS 1248416-43-4)
- N-(2-Chlorophenyl)-2-{[3-ethyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040632-44-7)
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- tert-Butyl 3-fluoro-4-hydroxyazepane-1-carboxylate (CAS 1209780-39-1)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
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