2-(3-Fluoro-4-methoxyphenyl)-2-oxoacetic acid CAS 455-72-1
| CAS No. | 455-72-1 |
| Molecular Formula | C9H7FO4 |
| Molecular Weight | 198.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3-Fluoro-4-methoxyphenyl)-2-oxoacetic acid.
2-(3-Fluoro-4-methoxyphenyl)-2-oxoacetic acid (CAS 455-72-1) is a high-purity analytical reference standard with the molecular formula C9H7FO4 and a molecular weight of 198.15 g/mol.
The molecular framework of 2-(3-Fluoro-4-methoxyphenyl)-2-oxoacetic acid (C9H7FO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(3-Fluoro-4-methoxyphenyl)-2-oxoacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7FO4 |
| Molecular Weight | 198.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
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Recommended Standards
- 2-(2-Fluoroacetoxy)benzoic acid (CAS 364-71-6)
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- 2-(CARBOXYMETHYL)-5-FLUOROBENZOIC ACID (CAS 583880-95-9)
- tert-Butyl 2-[(methanesulfonyloxy)methyl]pyrrolidine-1-carboxylate (CAS 1092681-48-5)
- 4-(2,3-Dihydrobenzofuran-5-yl)pyrrolidin-2-one (CAS 1367023-57-1)
- 3-(3-Nitrophenyl)pyridine (CAS 4282-50-2)
- Tert-butyl 9-fluoro-2,6-diazaspiro[4.5]Decane-2-carboxylate (CAS 1889430-37-8)
- Methyl 4-[(3-pyrrolidinyloxy)methyl]benzoatehydrochloride (CAS 1220034-80-9)
- (S)-2-Chloro-N-ethyl-N-(1-methylpyrrolidin-3-yl)acetamide (CAS 1353996-21-0)
- Methyl 2-oxa-5-azabicyclo[2.2.1]Heptane-4-carboxylate hydrochloride (CAS 2137451-00-2)
- N-methyl-5-phenyl-1,3-thiazol-2-amine (CAS 1344198-25-9)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-benzylpropanoic acid (CAS 828254-16-6)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
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