6-Iodo-N-phenylquinazolin-4-amine CAS 455887-98-6
| CAS No. | 455887-98-6 |
| Molecular Formula | C14H10IN3 |
| Molecular Weight | 347.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Iodo-N-phenylquinazolin-4-amine (C14H10IN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Iodo-N-phenylquinazolin-4-amine (CAS 455887-98-6) is a high-purity analytical reference standard with the molecular formula C14H10IN3 and a molecular weight of 347.15 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10IN3 |
| Molecular Weight | 347.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- N-(5-iodopyridin-2-yl)-2-morpholinoacetamide (CAS 343373-24-0)
- 3-(2-(3-Iodophenyl)-2-oxoethyl)benzonitrile (CAS 898784-37-7)
- tert-Butyl (5-bromo-4-(trifluoromethyl)thiazol-2-yl)carbamate (CAS 2806012-42-8)
- 3-(2-(2-Iodophenyl)-2-oxoethyl)benzonitrile (CAS 898784-35-5)
- Virodhamine (CAS 287937-12-6)
- 2-((Trifluoromethyl)thio)phenol (CAS 33185-56-7)
- 2,3-Difluoro-6-(phenylmethoxy)benzaldehyde (CAS 947279-31-4)
- 6-(Cyclohexylmethoxy)-N-phenyl-1H-purin-2-amine (CAS 444722-80-9)
- Fenclozic Acid (CAS 17969-20-9)
- (5-Nitrofuran-2-yl)methyl dipropylcarbamodithioate (CAS 57905-46-1)
- Labetalol Impurity 21 (CAS 33254-88-5)
- methyl 2-(7-amino-2,3-dihydro-1,4-benzodioxin-6-yl)acetate hydrochloride (CAS 1797842-87-5)
- (E)-4-(2-(5,5-Dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl)vinyl)benzoic acid (CAS 215030-90-3)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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