(±)-trans-1-(tert-Butoxycarbonyl)-3-(4-chlorophenyl)piperidine-4-carboxylic acid CAS 455954-83-3
| CAS No. | 455954-83-3 |
| Molecular Formula | C17H22ClNO4 |
| Molecular Weight | 339.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (±)-trans-1-(tert-Butoxycarbonyl)-3-(4-chlorophenyl)piperidine-4-carboxylic acid is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (±)-trans-1-(tert-Butoxycarbonyl)-3-(4-chlorophenyl)piperidine-4-carboxylic acid (CAS 455954-83-3), a certified reference material (molecular formula C17H22ClNO4, MW 339.81 g/mol) for analytical method development and quality control.
The molecular framework of (±)-trans-1-(tert-Butoxycarbonyl)-3-(4-chlorophenyl)piperidine-4-carboxylic acid (C17H22ClNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (±)-trans-1-(tert-Butoxycarbonyl)-3-(4-chlorophenyl)piperidine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H22ClNO4 |
| Molecular Weight | 339.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (E)-3-((tert-Butoxycarbonyl)(isopropyl)amino)-2-(4-chlorophenyl)acrylic acid (CAS 1489004-27-4)
- (2S,4R)-1-(tert-butoxycarbonyl)-4-(2-chlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 959581-51-2)
- 1-(Tert-butyl) 3-methyl (3R,4S)-4-(4-chlorophenyl)pyrrolidine-1,3-dicarboxylate (CAS 1432675-14-3)
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-(3-chlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 959576-36-4)
- 3-(2,6-Dimethoxyphenyl)propanoic acid (CAS 6683-69-8)
- 2-Methyl-5-(2-nitrophenyl)thiophene (CAS 96919-45-8)
- Pirimicarb-desamido-desmethyl (CAS 78195-30-9)
- 4-Hydroxy estrone 1-N7-guanine (CAS 178971-92-1)
- N-(4-Chlorophenyl)-2,2-difluoro-2-phenoxyacetamide (CAS 338791-86-9)
- N′-[[1-(4-chlorophenyl)-1H-tetrazol-5-yl]methyl]-N,N-dimethylsulfamide (CAS 897623-86-8)
- Ethyl 3-cyano-3-(4-methoxyphenyl)-2-oxopropanoate (CAS 41339-41-7)
- 3-(4-Methoxyphenyl)pentan-3-ol (CAS 17138-75-9)
- N-(3,4-Dichlorophenyl)formamide (CAS 5470-15-5)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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