5-Amino-6-(methylamino)pyrimidin-4(3H)-one CAS 45751-74-4
| CAS No. | 45751-74-4 |
| Molecular Formula | C5H8N4O |
| Molecular Weight | 140.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-6-(methylamino)pyrimidin-4(3H)-one.
5-Amino-6-(methylamino)pyrimidin-4(3H)-one (CAS 45751-74-4), molecular formula C5H8N4O and molecular weight 140.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, 5-Amino-6-(methylamino)pyrimidin-4(3H)-one is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 140.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Amino-6-(methylamino)pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H8N4O |
| Molecular Weight | 140.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-(3-amino-1H-pyrazol-1-yl)acetamide (CAS 1003011-28-6)
- 5-Amino-6-(methylamino)pyrimidin-2(1H)-one (CAS 104096-91-5)
- 5-Amino-6-methoxypyridin-2-ol (CAS 1094935-67-7)
- 6-Amino-5-methoxypyridin-3-ol (CAS 1105933-56-9)
- 3-Amino-1-methyl-1h-pyrazole-5-carboxamide (CAS 1129541-01-0)
- 4-Amino-3-methoxypyridine 1-oxide (CAS 115282-74-1)
- 2-(4-Amino-1h-pyrazol-1-yl)acetamide (CAS 1152939-86-0)
- 2-Amino-N-(1H-pyrazol-4-yl)acetamide (CAS 1154594-08-7)
Recommended Standards
- 5-Amino-4-methyl-1H-pyrazole-1-carboxamide (CAS 77668-02-1)
- 5-Amino-N-methyl-1H-pyrazole-1-carboxamide (CAS 54408-76-3)
- 5-Amino-2-methyl-1H-pyrrole-3-carboxylic acid (CAS 802004-21-3)
- 5-cyano-1H-pyrrole-2-carboxylic acid (CAS 854044-30-7)
- 3-Amino-2,3-dihydrobenzo[b][1,4]oxazepin-4(5h)-one (CAS 94590-46-2)
- Pyrido[2,3-b]pyrazin-3(4H)-one (CAS 35252-02-9)
- 5-Methyl-1H-indole-2-carbonitrile (CAS 1522608-25-8)
- 2-Methoxycyclopropanamine hydrochloride (CAS 1046469-17-3)
- 1-Methyl-5-(2,2,2-trifluoroethoxy)-1H-pyrazole-4-carboxylic acid (CAS 1437482-19-3)
- 2-bromo-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 1397287-45-4)
- Lanthanum nickel (CAS 12196-72-4)
- 1-(4-Amino-6-chloro-3-pyridyl)ethanone (CAS 1393559-79-9)
- 4-(2H-1,3-Benzodioxol-5-yl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 779316-39-1)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com