5-[2-(trimethylsilyl)ethynyl]pyridin-2-amine CAS 457628-40-9
| CAS No. | 457628-40-9 |
| Molecular Formula | C10H20N2Si |
| Molecular Weight | 196.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-[2-(trimethylsilyl)ethynyl]pyridin-2-amine (CAS 457628-40-9), molecular formula C10H20N2Si and molecular weight 196.36 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-[2-(trimethylsilyl)ethynyl]pyridin-2-amine (C10H20N2Si) contains a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 196.36 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H20N2Si |
| Molecular Weight | 196.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related trimethylsilyl Standards
- 2-[2-(trimethylsilyl)ethynyl]pyridin-4-amine (CAS 667932-22-1)
- p-(Trimethylsilyl)phenylmethanethiol (CAS 57337-85-6)
- 3-(Trimethylsilyl)propane-1-sulfonic acid (CAS 18173-90-5)
- 4-((Trimethylsilyl)ethynyl)thiazol-2-amine (CAS 329203-88-5)
- 1-((Trimethylsilyl)ethynyl)cyclobutane-1-carboxylic acid (CAS 1268810-14-5)
- 1-(3-(Trimethylsilyl)prop-2-yn-1-yl)cyclopropane-1-carboxylic acid (CAS 2502205-92-5)
- 2-[(Trimethylsilyl)ethynyl]aniline (CAS 103529-16-4)
- 2-Methyl-4-[2-(trimethylsilyl)ethynyl]-1,3-thiazole (CAS 329203-85-2)
Recommended Standards
- 4-(2-trimethylsilylethynyl)phenol (CAS 88075-18-7)
- Tetradec-7-ene (CAS 10374-74-0)
- 7-Methylenetridecane (CAS 19780-80-4)
- 2-(tert-Butyldimethylsilyl)-1-methyl-1H-imidazole (CAS 160425-48-9)
- (E)-1-(4-Chlorophenyl)-N-phenylmethanimine (CAS 1613-95-2)
- 4-Cyclopropyl-2-isobutylpyrimidine-5-carboxylic acid (CAS 1249972-15-3)
- {[2-(4-fluorophenyl)-1,3-thiazol-4-yl]methyl}(methyl)amine (CAS 1153070-05-3)
- GDP-Mannose (CAS 3123-67-9)
- A-methyl-1h-pyrrole-2-acetic acid methyl ester (CAS 92454-10-9)
- 5-Chloro-4-(methylamino)pyridine-3-sulfonamide (CAS 1352506-55-8)
- Copper pyrithione (CAS 154592-20-8)
- Ethyl 2-oxo-1,2-dihydro-1,6-naphthyridine-4-carboxylate (CAS 1054479-45-6)
- 6-(2-Nitrophenyl)-2,3-dihydropyridazin-3-one (CAS 147849-76-1)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com