3-Methyl-5-(pyrazin-2-yl)isoxazole CAS 457654-03-4
| CAS No. | 457654-03-4 |
| Molecular Formula | C8H7N3O |
| Molecular Weight | 161.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Methyl-5-(pyrazin-2-yl)isoxazole (CAS 457654-03-4), a certified reference material (molecular formula C8H7N3O, MW 161.16 g/mol) for analytical method development and quality control.
3-Methyl-5-(pyrazin-2-yl)isoxazole (C8H7N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Methyl-5-(pyrazin-2-yl)isoxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7N3O |
| Molecular Weight | 161.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 5-(Pyrazin-2-yl)-1H-pyrazol-3-amine (CAS 1232224-86-0)
- 3-(Pyrazin-2-yl)-1h-pyrazol-4-amine (CAS 896467-28-0)
- N-(1-(pyrazin-2-yl)ethyl)prop-2-yn-1-amine (CAS 1341366-97-9)
- 3-(Pyrazin-2-yl)isoxazol-5-amine (CAS 1710853-32-9)
- 5-Methyl-3-(pyrazin-2-yl)-1,2,4-oxadiazole (CAS 51285-07-5)
- 5-Pyrazin-2-yl-1,2,4-oxadiazol-3-amine (CAS 1086378-64-4)
- 717848-18-5 5-(Pyrazin-2-yl)-1,3,4-oxadiazol-2-amine DTXSID70649263 (CAS 717848-18-5)
- N-(Pyrazin-2-yl)cyclopropanecarboxamide (CAS 681250-02-2)
Recommended Standards
- 3-Methyl-4h-pyrido[2,1-c][1,2,4]triazin-4-one (CAS 33919-37-8)
- 3-Methyl-5-(pyridazin-4-yl)isoxazole (CAS 39123-41-6)
- 3-Methyl-3H-imidazo[4,5-c]pyridine-2-carbaldehyde (CAS 57805-99-9)
- 3-Methylbenzo[d][1,2,3]triazin-4(3H)-one (CAS 22305-44-8)
- 5-(Benzenesulfonyl)-4-(2-chlorophenyl)-2-phenylpyrimidine (CAS 339107-55-0)
- Alpha-amino-cyclobutaneacetic acid tert-butyl ester (CAS 126181-43-9)
- 6-Chloro-3-(difluoromethyl)-5-nitropicolinonitrile (CAS 1804674-18-7)
- 1142199-04-9 (4E)-3-(Chloromethyl)-4-(2,4-dimethoxybenzylidene)isoxazol-5(4H)-one MFCD12027787 (CAS 1142199-04-9)
- 7-chloro-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 33017-86-6)
- 3-(4-Chlorophenyl)-4,5-dihydroisoxazole-5-carbonitrile (CAS 1173119-75-9)
- (2E)-Heptenoic acid methyl ester (CAS 38693-91-3)
- 3-Ethoxy-4-(pyrimidin-5-yl)-1,2,5-thiadiazole (CAS 287472-28-0)
- tert-Butyl (2S,5R)-5-hydroxy-2-methylpiperidine-1-carboxylate (CAS 2081972-05-4)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
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