3-Methylene-cyclopropane-1,2-dicarboxylic acid CAS 45786-15-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methylene-cyclopropane-1,2-dicarboxylic acid.

CATO supplies 3-Methylene-cyclopropane-1,2-dicarboxylic acid (CAS 45786-15-0), a certified reference material (molecular formula C6H6O4, MW 142.11 g/mol) for analytical method development and quality control.

The molecular framework of 3-Methylene-cyclopropane-1,2-dicarboxylic acid (C6H6O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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