3-Chloro-5-phenylisothiazole-4-carboxamide CAS 457960-33-7
| CAS No. | 457960-33-7 |
| Molecular Formula | C10H7ClN2OS |
| Molecular Weight | 238.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Chloro-5-phenylisothiazole-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-Chloro-5-phenylisothiazole-4-carboxamide (CAS 457960-33-7) is a high-purity analytical reference standard with the molecular formula C10H7ClN2OS and a molecular weight of 238.69 g/mol.
3-Chloro-5-phenylisothiazole-4-carboxamide (C10H7ClN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2OS |
| Molecular Weight | 238.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- Methyl (S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylate dihydrochloride (CAS 114786-39-9)
- Pyrido[2,3-d]pyridazin-5(6H)-one, 8-(1-methylethyl)-2-(trifluoromethyl)- (CAS 2890563-24-1)
- 2-(Methylthio)-5-(5-nitrofuran-2-yl)-1,3,4-thiadiazole (CAS 3237-63-6)
- Benidipine Impurity 78 (CAS CATO-C4X-112078)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com