1,2-Bis(4-fluorophenyl)ethane CAS 458-76-4

Purity 97%+In StockPharmaceutical Standards
CAS No.458-76-4
Molecular FormulaC14H12F2
Molecular Weight218.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,2-Bis(4-fluorophenyl)ethane CAS 458-76-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2-Bis(4-fluorophenyl)ethane.

CATO supplies 1,2-Bis(4-fluorophenyl)ethane (CAS 458-76-4), a certified reference material (molecular formula C14H12F2, MW 218.24 g/mol) for analytical method development and quality control.

Owing to fluorine substitution, a polycyclic aromatic system, 1,2-Bis(4-fluorophenyl)ethane is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 218.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1,2-Bis(4-fluorophenyl)ethane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H12F2
Molecular Weight218.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing

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