(Difluoromethoxy)benzene CAS 458-92-4
| CAS No. | 458-92-4 |
| Molecular Formula | C7H6F2O |
| Molecular Weight | 144.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(Difluoromethoxy)benzene (C7H6F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(Difluoromethoxy)benzene (CAS 458-92-4), molecular formula C7H6F2O and molecular weight 144.12 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (Difluoromethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6F2O |
| Molecular Weight | 144.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- 3-(Difluoromethoxy)pyridine (CAS 1209729-90-7)
- 4-(Difluoromethoxy)pyridine (CAS 1210387-26-0)
- 2-(Difluoromethoxy)pyridine (CAS 865075-07-6)
- 3-(Difluoromethoxy)-5-methyl-1H-pyrazole (CAS 2108002-48-6)
- 4-(DIFLUOROMETHOXY)BUTAN-1-OL (CAS 863008-52-0)
- (R)-2-(difluoromethoxy)propanoic acid (CAS 1604260-95-8)
- (S)-2-(Difluoromethoxy)propanoic acid (CAS 1604374-53-9)
- 2-(difluoromethoxy)-2-methylpropan-1-amine (CAS 1497338-38-1)
Recommended Standards
- (2,6-Difluoropyridin-4-yl)methanamine (CAS 2604327-04-8)
- 1-(1,1-Dimethylethyl) 2-methyl (2S,4S)-4-fluoro-5-oxo-1,2-pyrrolidinedicarboxylate (CAS 899898-94-3)
- (2,5-Difluorophenyl)methanol (CAS 75853-20-2)
- 1,3-Diamino-2,5-difluorobenzene (CAS 25170-73-4)
- 4-Amino-1H-pyrrolo[3,2-c]pyridine (CAS 60290-23-5)
- Tert-butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate hydrochloride (CAS 1185722-79-5)
- 7-(Difluoromethoxy)-2-fluorobenzo[d]thiazole (CAS 1261812-79-6)
- 2-(4-Fluorobenzoyl)-4-methylpyridine (CAS 497854-55-4)
- N-Ethyl-N-methylcyclohexanamine (CAS 57880-93-0)
- 2-(2-Amino-4,5-dimethyl-6-oxopyrimidin-1(6H)-yl)-N-(2-methoxybenzyl)acetamide (CAS 1251621-52-9)
- Ethyl 4-oxo-4-(((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)amino)butanoate (CAS 899745-40-5)
- (5-Methyl-4-nitro-1H-pyrazol-1-yl)acetic acid (CAS 1001611-09-1)
- 7-Fluoro-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-6-carbaldehyde (CAS 1095276-16-6)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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