3-Methyl-4-nitro-isothiazole-5-carboxylic acid CAS 4592-53-4
| CAS No. | 4592-53-4 |
| Molecular Formula | C5H4N2O4S |
| Molecular Weight | 188.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Methyl-4-nitro-isothiazole-5-carboxylic acid (CAS 4592-53-4), a certified reference material (molecular formula C5H4N2O4S, MW 188.16 g/mol) for analytical method development and quality control.
3-Methyl-4-nitro-isothiazole-5-carboxylic acid (C5H4N2O4S) contains a carbohydrate-derived structure, an amide group, a sulfone group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Methyl-4-nitro-isothiazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4N2O4S |
| Molecular Weight | 188.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- 3-Fluoro-2-(1h-1,2,4-triazol-1-yl)benzonitrile (CAS 870562-65-5)
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- 3-(1-fluoro-2-methylpropan-2-yl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 2925379-34-4)
- 4-(Methoxycarbonyl)-1,2,5-thiadiazole-3-carboxylic acid (CAS 90993-85-4)
- 4,5-Dichloro-2-(chloromethyl)pyridazin-3(2H)-one (CAS 51356-03-7)
- (Z)-1-nitro-4-styrylbenzene (CAS 6624-53-9)
- 1-(2-Methoxy-5-(trifluoromethyl)phenyl)propan-2-one (CAS 1354819-39-8)
- (S)-2-(1-aminoethyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (CAS 1431699-63-6)
- 2-(4-Allyl-5-((4-bromobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 578760-93-7)
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- 3-((2-Bromophenyl)amino)propanoic acid (CAS 38470-20-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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