(5-Formyl-2-(trifluoromethoxy)phenyl)boronic acid CAS 459810-97-0
| CAS No. | 459810-97-0 |
| Molecular Formula | C8H6BF3O4 |
| Molecular Weight | 233.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(5-Formyl-2-(trifluoromethoxy)phenyl)boronic acid (CAS 459810-97-0), molecular formula C8H6BF3O4 and molecular weight 233.94 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (5-Formyl-2-(trifluoromethoxy)phenyl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (5-Formyl-2-(trifluoromethoxy)phenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BF3O4 |
| Molecular Weight | 233.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Formyl Standards
- (2-Formyl-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1218790-89-6)
- (3-Formyl-4-(trifluoromethoxy)phenyl)boronic acid (CAS 1310383-91-5)
- 2-Formyl-3-(trifluoromethoxy)phenyboronic acid (CAS 1451392-92-9)
- (3-Formyl-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1451393-39-7)
- 3-Formyl-5-(trifluoromethoxy)benzoic acid (CAS 2167993-22-6)
- 4-Formyl-3-(trifluoromethoxy)benzoic acid (CAS 2168813-13-4)
- 5-Formyl-2-(trifluoromethoxy)benzoic acid (CAS 2167732-24-1)
- Methyl 4-formyl-7-methoxy-1-benzofuran-2-carboxylate (CAS 59254-16-9)
Recommended Standards
- 1,5-Dibromopentane-1,1,5,5-d4 (CAS 1219803-90-3)
- 3-Carboxy-5-(trifluoromethyl)phenylboronic acid (CAS 1451393-22-8)
- 3-Ethoxy-4-(trifluoromethyl)phenylboronic acid (CAS 1026796-35-9)
- 2,6-Dichloro-3-fluoro-5-(trifluoromethyl)pyridine (CAS 1099598-11-4)
- 3-bromo-5-(prop-1-yn-1-yl)pyridine (CAS 917772-69-1)
- 4-(Aminomethyl)-6-(difluoromethyl)-3-(trifluoromethyl)pyridine-2-sulfonyl chloride (CAS 1361887-11-7)
- 1H-Pyrazole, 1-(1-phenylpropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- (CAS 1629171-81-8)
- 3-Cyclopropoxy-2-fluorobenzamide (CAS 1243321-69-8)
- Methyl 2-(1-methyl-4-oxo-1,4-dihydroquinolin-3-yl)benzoate (CAS 294184-16-0)
- 1-(3-Fluorobenzyl)-N-(3-methylpyridin-2-yl)-6-oxo-1,6-dihydropyridazine-3-carboxamide (CAS 1040664-11-6)
- 2-Chloro-6-ethyl-1,3-benzothiazole (CAS 890091-97-1)
- 3-(1-Phenyl-1H-1,2,4-triazol-5-yl)piperidine (CAS 1708255-08-6)
- 3,6-Dimethylundecane (CAS 17301-28-9)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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