1-(Methylamino)isoquinoline CAS 46000-11-7
| CAS No. | 46000-11-7 |
| Molecular Formula | C10H10N2 |
| Molecular Weight | 158.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Methylamino)isoquinoline.
CATO supplies 1-(Methylamino)isoquinoline (CAS 46000-11-7), a certified reference material (molecular formula C10H10N2, MW 158.20 g/mol) for analytical method development and quality control.
1-(Methylamino)isoquinoline (C10H10N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10N2 |
| Molecular Weight | 158.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 2 |
Related Methylamino Standards
- 6-(methylamino)pyridazine-3-carboxamide (CAS 1251357-92-2)
- 2-(methylamino)-1-(morpholin-4-yl)ethan-1-one (CAS 41458-73-5)
- 2-(methylamino)pyridine-4-carboxylic acid (CAS 876717-53-2)
- 3-Methyl-5-(2-(methylamino)ethyl)oxazolidin-2-one (CAS 745723-76-6)
- 4-(Methylamino)piperidine-4-carboxylic acid (CAS 790616-58-9)
- 2-(Methylamino)-1,3-thiazole-4-carboxylic acid (CAS 1199216-02-8)
- 2-(Methylamino)-1,3-thiazole-5-carboxylic acid (CAS 1393525-02-4)
- 4-(Methylamino)-1,2,5-thiadiazole-3-carboxamide (CAS 89281-53-8)
Recommended Standards
- 1-(Aminomethyl)isoquinoline (CAS 40615-08-5)
- 1-(m-Tolyl)imidazole (CAS 25364-43-6)
- 1-(Allyloxy)-2-ethynylbenzene (CAS 66021-96-3)
- 1-(o-Tolyl)-1H-imidazole (CAS 25371-93-1)
- 6-Methoxy-N-methylpyridine-2-carboxamide (CAS 1356543-02-6)
- 1-[(1-Chlorocyclobutyl)sulfinyl]-4-methylbenzene (CAS 1221171-44-3)
- 3-Bromo-3-ethylpentane (CAS 73908-04-0)
- 6-Bromo-4-chloronicotinaldehyde (CAS 1060811-24-6)
- 2-(([1,2,4]triazolo[4,3-a]pyridin-3-yloxy)methyl)-8-methyl-4h-pyrido[1,2-a]pyrimidin-4-one (CAS 949740-29-8)
- 2,6-Dimorpholinopyridin-4-amine (CAS 1075215-74-5)
- Ceritinib Impurity 80 (CAS CATO-C4X-104880)
- 4-(Methoxycarbonyl)-1H-indazole-3-carboxylic acid (CAS 393553-44-1)
- ethyl 8-methyl-4-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate (CAS 2044722-71-4)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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