Ethyl 2-Chlorooxazole-4-carboxylate CAS 460081-18-9
| CAS No. | 460081-18-9 |
| Molecular Formula | C6H6ClNO3 |
| Molecular Weight | 175.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 2-Chlorooxazole-4-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 175.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Ethyl 2-Chlorooxazole-4-carboxylate (CAS 460081-18-9), a certified reference material (molecular formula C6H6ClNO3, MW 175.57 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO3 |
| Molecular Weight | 175.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 5-chlorooxazole-4-carboxylate (CAS 1823403-24-2)
- Ethyl 2-Chlorooxazole-5-carboxylate (CAS 862599-47-1)
- Ethyl 4-chlorooxazole-5-carboxylate (CAS 2095432-64-5)
- Methyl 2-chlorooxazole-4-carboxylate (CAS 934236-35-8)
- Methyl 2-Chlorooxazole-5-carboxylate (CAS 934236-41-6)
- 5-Chlorooxazole-4-carboxylic acid (CAS 1240601-37-9)
- 2-Chlorooxazole-5-carboxylic acid (CAS 1555623-55-6)
- 2-Chlorooxazole-4-carboxylic Acid (CAS 706789-07-3)
Recommended Standards
- 5-(Methoxymethyl)isoxazole-3-carbonyl chloride (CAS 80173-69-9)
- 5-(Chloromethyl)-1-methyl-2-nitroimidazole (CAS 87544-76-1)
- 2-Chloro-N-(4-methyl-1,2,5-oxadiazol-3-yl)acetamide (CAS 32545-22-5)
- Ethyl 5-chloro-1,2-oxazole-3-carboxylate (CAS 343566-56-3)
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- n-(4-Bromo-2-fluorophenyl)prop-2-enamide (CAS 335275-68-8)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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