2-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)benzo[d]thiazole CAS 460994-82-5
| CAS No. | 460994-82-5 |
| Molecular Formula | C17H16ClN3O2S2 |
| Molecular Weight | 393.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)benzo[d]thiazole (CAS 460994-82-5) is a high-purity analytical reference standard with the molecular formula C17H16ClN3O2S2 and a molecular weight of 393.91 g/mol.
2-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)benzo[d]thiazole (C17H16ClN3O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)benzo[d]thiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16ClN3O2S2 |
| Molecular Weight | 393.91 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 1-(2-(4-Chlorophenyl)quinolin-4-yl)-N-ethylpiperidine-4-carboxamide (CAS 103914-11-0)
- 2-[(4-Chlorophenyl)sulfanyl]-N-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]acetamide (CAS 478260-44-5)
- 6-(3-Chlorophenyl)-4-phenyl-2-(2-(piperidin-1-yl)ethyl)pyridazin-3(2H)-one (CAS 23348-28-9)
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- 7-(3-Chlorophenyl)-2-(3,4-dihydroisoquinolin-2(1H)-yl)thieno[3,2-d]pyrimidin-4-ol (CAS 1243090-25-6)
- 6-(4-Chlorophenyl)-2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 338751-64-7)
- Methyl 3-(2-(4-(3-chlorophenyl)piperazin-1-yl)acetamido)thiophene-2-carboxylate (CAS 477887-73-3)
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Recommended Standards
- (5-Chlorothiophen-2-yl)(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1788681-94-6)
- 2-Chloro-n-[3-(4-cyclohexylphenyl)-1-phenyl-1h-pyrazol-5-yl]acetamide (CAS 956374-40-6)
- 4-Chloro-N-cyclohexyl-N-[(4-methoxyphenyl)methyl]benzene-1-sulfonamide (CAS 1881331-32-3)
- 4-Chloro-N-(2-(4-(methylsulfonyl)piperazin-1-yl)phenyl)benzamide (CAS 478260-31-0)
- 3-((4-Cyclohexylphenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 882748-69-8)
- 2-(Dimethylamino)benzene-1,4-diol (CAS 50564-14-2)
- (1R,3R)-3-(trifluoromethyl)cyclohexan-1-amine (CAS 764594-44-7)
- 2-Amino-3-phenylbutanoic acid (CAS 2260-12-0)
- (R)-2-Methyl-N-(4-nitrophenyl)propane-2-sulfinamide (CAS 1372133-70-4)
- 5-Fluoro-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1190322-05-4)
- 4-(Aminomethyl)-5-nitrobenzene-1,2-diol (CAS 887582-24-3)
- 1-(Carboxylatomethyl)-3-(carboxymethyl)-1H-1,3-benzodiazol-3-ium (CAS 938058-97-0)
- 1-(4,5-Dimethyl-4h-1,2,4-triazol-3-yl)cyclopentan-1-amine (CAS 1247594-20-2)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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