4-(Aminosulfonyl)benzenesulfonyl chloride CAS 46249-41-6
| CAS No. | 46249-41-6 |
| Molecular Formula | C6H6ClNO4S2 |
| Molecular Weight | 255.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Aminosulfonyl)benzenesulfonyl chloride.
4-(Aminosulfonyl)benzenesulfonyl chloride (CAS 46249-41-6) is a high-purity analytical reference standard with the molecular formula C6H6ClNO4S2 and a molecular weight of 255.70 g/mol.
Based on its molecular formula C6H6ClNO4S2, 4-(Aminosulfonyl)benzenesulfonyl chloride contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 255.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Aminosulfonyl)benzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO4S2 |
| Molecular Weight | 255.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Aminosulfonyl Standards
- N-[3-(aminosulfonyl)-4-ethoxyphenyl]acetamide (CAS 953731-81-2)
- Methyl 2-(aminosulfonyl)-4-chlorobenzoate (CAS 14065-45-3)
- 3-(Aminosulfonyl)-4-chlorobenzoic acid hydrazide (CAS 5378-62-1)
- [3-(aminosulfonyl)-5-fluoro-4-methoxyphenyl]acetic acid (CAS 926236-77-3)
- 3-(Aminosulfonyl)-4-(1-methylethyl)benzoic acid (CAS 59815-30-4)
- 1-(aminosulfonyl)piperidin-4-yl trifluoroacetate (CAS 1000932-69-3)
- Ethyl 6-(aminosulfonyl)-1-cyclohexene-1-carboxylate (CAS 2119574-69-3)
- 5-aminosulfonyl-1-methyl pyrazole-4-carboxylic-acid ethyl ester (CAS 88398-81-6)
Recommended Standards
- 4-(2-Chlorophenyl)-3-phenyl-4H-1,2,4-triazole (CAS 88032-11-5)
- 4-Chloro-2-nitro-5-(piperidin-1-yl)aniline (CAS 87200-61-1)
- 3-Sulfamoylbenzenesulfonyl chloride (CAS 62646-47-3)
- 4-Chloro-2-phenylquinolin-7-ol (CAS 332181-62-1)
- N,N-diisopropylethylamine hydrochloride (CAS 36340-89-3)
- 2-(Hydroxymethyl)-2-(4H-1,2,4-triazol-4-yl)propane-1,3-diol (CAS 1696720-09-8)
- 2-(3-Bromophenyl)-4-chloropyrimidine (CAS 97604-15-4)
- Ethyl 1-(2,2,2-trifluoroethyl)piperidine-3-carboxylate (CAS 937603-24-2)
- 1-((4-Hydroxyphenyl)imino)tetrahydro-1H-1lambda6-thiophene 1-oxide (CAS 1955493-41-0)
- methyl (E)-2-(tert-butoxycarbonylamino)-3-tetrahydropyran-4-yl-prop-2-enoate (CAS 1361215-56-6)
- (E)-3-(6-(4-bromophenyl)imidazo[2,1-b]thiazol-5-yl)-1-(pyridin-2-yl)prop-2-en-1-one (CAS 685106-67-6)
- Foritinib Impurity 16 (CAS CATO-C4X-331016)
- 2-Benzyl-5-butoxy-3,4-dihydroisoquinolin-1(2H)-one (CAS 850905-29-2)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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