1-(Naphthalen-1-yl)guanidine hydrochloride CAS 46273-15-8
| CAS No. | 46273-15-8 |
| Molecular Formula | C11H11N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Naphthalen-1-yl)guanidine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(Naphthalen-1-yl)guanidine hydrochloride (CAS 46273-15-8), molecular formula C11H11N3HCl and molecular weight 221.69 g/mol, is a CATO reference standard with documented purity and traceability.
1-(Naphthalen-1-yl)guanidine hydrochloride (C11H11N3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11N3 HCl |
| Molecular Weight | 221.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Naphthalen Standards
- 2-(Naphthalen-2-yl)isonicotinic acid (CAS 100004-92-0)
- 2-(Naphthalen-1-yl)isonicotinic acid (CAS 100004-93-1)
- 1-Methyl-2-(naphthalen-1-yl)-1H-imidazole (CAS 1001755-52-7)
- 4,4'-Bis(10-(naphthalen-1-yl)anthracen-9-yl)-1,1'-biphenyl (CAS 1002328-32-6)
- 4-(Naphthalen-1-yl)piperidin-4-ol (CAS 100240-14-0)
- 4-(naphthalen-1-yl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 100240-18-4)
- Sodium 2-(naphthalen-2-yloxy)acetate (CAS 10042-71-4)
- 1-(Naphthalen-1-yl)ethan-1-one oxime (CAS 100485-51-6)
Recommended Standards
- 2,4,6-Tris(difluoromethyl)-1,3,5-triazine (CAS 369-22-2)
- N'-methyl-N'-(2-(methylthio)quinazolin-4-yl)thiophene-2-carbohydrazide (CAS 341968-19-2)
- n1-(3-Fluorobenzyl)-n3,n3-dimethylpropane-1,3-diamine (CAS 1021064-50-5)
- 2,6-Bis[[(R)-2-[hydroxy(diphenyl)methyl]-1-pyrrolidinyl]methyl]-4-methylphenol (CAS 877395-58-9)
- Paliperidone Impurity 19 (CAS 1388072-44-3)
- (2,4-Dimethoxyphenyl)(2-methoxyphenyl)methanone (CAS 33077-87-1)
- 2-(3-Butyryl-1H-indol-1-yl)acetic acid (CAS 892676-98-1)
- Titanium(III) fluoride (CAS 13470-08-1)
- tert-Butyl (1-(5-fluoropyrimidin-2-yl)ethyl)carbamate (CAS 1824210-92-5)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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