4-Bromo-2-(difluoromethyl)-thiophene CAS 463946-41-0
| CAS No. | 463946-41-0 |
| Molecular Formula | C8H7NS |
| Molecular Weight | 149.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-2-(difluoromethyl)-thiophene.
CATO supplies 4-Bromo-2-(difluoromethyl)-thiophene (CAS 463946-41-0), a certified reference material (molecular formula C8H7NS, MW 149.21 g/mol) for analytical method development and quality control.
4-Bromo-2-(difluoromethyl)-thiophene (C8H7NS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7NS |
| Molecular Weight | 149.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 4-Aminotetrahydrothiopyran 1,1-Dioxide (CAS 210240-20-3)
- 4-Methylbenzo[c]isothiazole (CAS 20728-41-0)
- 4-(sulfanylmethyl)benzonitrile (CAS 51776-12-6)
- 4-Methylbenzothiazole (CAS 3048-48-4)
- 3-Bromo-4-(trifluoromethoxy)benzamide (CAS 914636-29-6)
- 2-Chloro-3-(difluoromethyl)-4,5-diiodopyridine (CAS 1805329-84-3)
- 3-[2-(2,5-Dimethyl-1H-pyrrol-1-yl)ethyl]-1H-indole 4284AF 95399-28-3 C16H18N2 (CAS 95399-28-3)
- N-Benzyl-N’-(4-aminoÂbenzÂoylÂ)bispidine (CAS 83991-25-7)
- Spiro[2.4]Heptan-4-amine hydrochloride (CAS 2060052-47-1)
- tert-Butyl 7-bromo-4-chloro-1-oxoisoindoline-2-carboxylate (CAS 2628351-94-8)
- 2-(2-Methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 1429903-98-9)
- 7-Methyl-3-oxo-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 1133-31-9)
- n-[2-methyl-1-(2h-1,2,3,4-tetrazol-5-yl)propyl]benzamide (CAS 1315368-47-8)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
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