Isofluorane Impurity N2 CAS 464-00-6
| CAS No. | 464-00-6 |
| Molecular Formula | C2H3ClF2O |
| Molecular Weight | 116.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isofluorane Impurity N2.
As a process- or degradation-related impurity, Isofluorane Impurity N2 (CAS 464-00-6, C2H3ClF2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Isofluorane Impurity N2 is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 116.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C2H3ClF2O |
| Molecular Weight | 116.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Isofluorane Standards
Recommended Standards
- 9002-83-9 Chlorotrifluoroethene, homopolymer Ethene, chlorotrifluoro-, homopolymer Polychlorotrifluoroethylene Ethylene, chlorotrifluoro-, polymers (8CI) Halocarbon oil, series 27-S Kel-F Safetol 3.1 oil Ethene, 1-chloro-1,2,2-trifluoro-, homopolymer F 3M 11 F 12 F 12FD 13FM 4LF F 3 (Vinyl polymer) 3.1 Oil Aclar 22A Aclar 33C Chlorotrifluoroethene homopolymer Chlorotrifluoroethylene homopolymer Chlorotrifluoroethylene polymer Chlorotrifluoroethylene polymers Daifloil 10 Daifloil 100 Daifloil 20 Daifloil 3 Daifloil 50 Daiflon D 45S Daiflon M 300 Daiflon M 300P Daiflon ctf3-D 55P Daiflon ctfe Ekafluvin FL-G 100 FL-G 330 FL-G 35 FL-G 5 Fluorolon 3 Fluorolube S 30 Fluorolube 2000 Fluorolube 300/140 Fluorolube FS 5 Fluorolube GR 470 Fluoroplast F 3 Fluoroplast 3 Fluoroplast 3P Fluorothene Ftorlon F3 Ftorlon 3 Ftorlon 3M Ftoroplast 3 Ftoroplast 3P Halar 200 Halocarbon 3.1 oil Halocarbon oil 11-14 Halocarbon oil 11-21 Halocarbon oil 13-21 Halon Halon (polymer) Hostaflon Hostaflon C Kel-F 200 Kel-F 3 Kel-F 6061 Kel-F 81 Kel-F 90 Kel-F 95/5 Kel-S Mil-H-531119 MLO 81-125 MLO 83-322 MLO 87-347 Neosorb ND Plaskon CTFE Poly(chlorotrifluoroethene) Poly(monochlorotrifluoroethylene) Poly(trifluorochloroethylene) Poly(trifluoroethylene chloride) Poly(trifluoromonochloroethylene) Poly(trifluorovinyl chloride) Teflex TL 340 Trifluorochloroethylene polymer Voltalef Voltalef 10 Voltalef 202 Voltalef 300LD Voltalef 300UF Voltalef IS (CAS 9002-83-9)
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