2-Amino-4-methylthiophene-3-carboxamide CAS 4651-97-2

Purity 97%+In StockPharmaceutical Standards
CAS No.4651-97-2
Molecular FormulaC6H8N2OS
Molecular Weight156.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-4-methylthiophene-3-carboxamide CAS 4651-97-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 156.21 g/mol gives 2-Amino-4-methylthiophene-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Amino-4-methylthiophene-3-carboxamide (CAS 4651-97-2) is a high-purity analytical reference standard with the molecular formula C6H8N2OS and a molecular weight of 156.21 g/mol.

The molecular framework of 2-Amino-4-methylthiophene-3-carboxamide (C6H8N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Amino-4-methylthiophene-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H8N2OS
Molecular Weight156.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Nitrogen Atoms2
Sulfur Atoms1

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