4-Chlorothiazole-2-carbaldehyde CAS 466686-79-3
| CAS No. | 466686-79-3 |
| Molecular Formula | C4H2ClNOS |
| Molecular Weight | 147.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chlorothiazole-2-carbaldehyde (C4H2ClNOS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Chlorothiazole-2-carbaldehyde (CAS 466686-79-3), molecular formula C4H2ClNOS and molecular weight 147.58 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H2ClNOS |
| Molecular Weight | 147.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorothiazole Standards
- 4-Chlorothiazole-5-carbaldehyde (CAS 104146-17-0)
- 5-Chlorothiazole-4-carbaldehyde (CAS 1161865-60-6)
- 5-Chlorothiazole-2-carbaldehyde (CAS 59129-52-1)
- 4-Chlorothiazole-2-carbonitrile (CAS 1363383-13-4)
- 4-Chlorothiazole-5-carbonitrile (CAS 145383-72-8)
- 2-Chlorothiazole-4-carbonitrile (CAS 944124-72-5)
- 2-Chlorothiazole-4-carboxamide (CAS 928256-35-3)
- 2-Chlorothiazole-5-carboxamide (CAS 761454-63-1)
Recommended Standards
- 2-Chloro-4-formylthiazole (CAS 5198-79-8)
- 2-Chloro-1,3-thiazole-5-carboxaldehyde (CAS 95453-58-0)
- 5-Isothiazolecarbonyl chloride (CAS 3683-97-4)
- 1,3-Thiazole-4-carbonyl chloride (CAS 3745-79-7)
- 7-Methoxy-8-methyl-2-(4-(trifluoromethyl)thiazol-2-yl)quinolin-4-ol (CAS 1180493-97-3)
- Benzisothiazole-3-carboxylic Acid (CAS 40991-34-2)
- n-Phenyl-2-(piperidin-4-yl)azepane-1-carboxamide (CAS 1334148-71-8)
- 4-Chloro-3-methyl-5-phenylisoxazole (CAS 10557-76-3)
- Imidazole-1-sulfonyl Azide Hydrochloride (CAS 952234-36-5)
- (R)-2-(3,4-dimethoxyphenyl)-2-(methylamino)ethan-1-ol (CAS 1336325-28-0)
- 5-Methylbenzo[b]thiophen-2(3H)-one (CAS 73129-57-4)
- 9-Oxo-9H-fluorene-2,6-dicarboxylic acid (CAS 60505-55-7)
- (1S,3s)-3-(piperazin-1-yl)cyclobutan-1-ol (CAS 1033719-07-1)
- Peptide T (CAS 106362-32-7)
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